Director Global HEOR, Povetacicept

Job Description

Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group in Boston, MA.The Health Economics & Outcomes Research Director will lead HEOR strategies and execution of evidence generation that optimize the value proposition of Vertex's povetacicept assets through each stage of development, including launch and post-launch phases. This position reports to the Senior Director Global HEOR Kidney.

Key Duties and Responsibilities:

• Serves as the HEOR povetacicept Lead focusing on pipeline indications: pMN and/or gMG
• Develops the HEOR strategy for povetacicept from early development through product lifecycle
• Serves as HEOR lead to cross-functional and cross-regional teams to align strategic plans to stakeholder needs and represent the voice of HEOR
• Execute complex HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset value
• Gathers and synthesizes insights from Payers, KOLs and HEOR experts; stays current with scientific and policy trends and best practices and applies strategic and content expertise to strategy planning
• Supports the integration of HEOR evidence in health technology appraisal submissions for relevant assets
• Collaborates with the medical communications teams on publication strategy and ensure that dissemination of HEOR evidence is timely and has maximum impact
• Partners and works closely with Global Pricing and Market Access to support production of GVD and Value Narrative
• Collaborates closely with global brand marketing, clinical, and other functional teams to support and enhance access to marketed products across various regions and serves as HEOR lead to cross-functional teams
• Oversee the design and execution of HEOR studies and apply best practices for HEOR analyses, modeling and dissemination; ensures the highest quality standards for research and dissemination

Knowledge and Skills:

• Provides technical expertise in HEOR and able to formulate and lead creative research projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices
• Strong track record of publications in peer-reviewed journals demonstrating experience in evidence synthesis, patient reported outcomes, observational research, and health economic modeling
• Demonstrate capabilities to develop global strategic HEOR plans and execute studies with comprehensive understanding of clinical development strategies and trial designs
• Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development plans, to identify evidence gaps and formulate evidence generation strategies
• Market Access experience, including direct experience in making submissions to relevant payers and interacting with them is strongly desired (US and EX-US)
• Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences
• Broad and comprehensive understanding of the legal and regulatory environment of the pharmaceutical industry, demonstrated integrity on work-related compliance considerations and solid ethics

Education and Experience:

• Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline.
• Typically requires 10 years of experience in health economics and outcomes research, or directly-related field and industry, or the equivalent combination of education and experience

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com