Post-Doctoral Associate

This position involves research work to investigate pathological mechanisms and search for drug development for neurological diseases using animal models and related experimental techniques and technologies. The Grossman Center is involved in basic research in the field of Alzheimer's disease and traumatic brain injury. The research effort is looking at mechanisms of Alzheimer disease and Traumatic Brain Injury (TBI) pathogenesis in mouse models using biochemistry, cell biology and immunohistochemistry procedures and neuroanatomy knowledge and skills.

Major Duties:
(70%)- Perform study design and conduct:
o Maintain mouse colonies and set up study cohorts for research projects in the lab.
o Conduct animal study procedures, such as intracranial stereotaxic injection and Intraperitoneal (IP) drug delivery as well as animal behavior studies after training and supervision by principal investigator and/or senior lab staff.
o Prepare biological specimens (such as (Ribonucleic Acid) RNA, (Deoxyribonucleic Acid) DNA and proteins extracted from postmortem human or rodent brains, primary and immortalized cell cultures); quality control of these specimens using appropriate instrumentation; performs molecular cell biology and biochemical studies, such as immunoprecipitation, western blot analysis, immunohistochemistry and immunocytochemistry, high pressure liquid chromatography and mass spectrometry, tissue DNA extraction, quantitative PCR studies, etc.
o Develop data collection tools and collect data required by the study plan, e.g. conducts literature searches for methods and procedures specified by the principal investigator; plans and develops assays to evaluate experimental methods and techniques.

(15%)- Manage research results and prepare publication:
o Record descriptions of experiments, the timing involved, and the observations made. Compile and document results of experiments and prepares data in format which best illustrates the results (e.g. worksheet, graphs, tables, etc.) and assists in developing appropriate computer programs.
o Analysis of data obtained as a result of experiments performed, and preparation of laboratory reports to be submitted to the supervisor.
o Summarize project-related work through written and oral communications as well as prepare manuscripts for publications with the supervisor.

(10%)- Manage laboratory:
o Prepare summaries of techniques and procedures for inclusion in laboratory technical reports and publications.
o Develop improvements and modifications to established procedures to increase laboratory efficiency.
o Maintain research lab. Perform routine maintenance on laboratory equipment and maintaining laboratory in a neat, clean and orderly manner.

(5%)- Supervise lab staff, graduate students and interns:
o Train junior lab personnel such as technicians, interns and students rotating in the lab with experimental techniques and research tools.
o Supervise their performance during experimental activities and data analysis.
o Assist other lab colleagues in various project-related work and perform trouble shooting and problem-solving communication with others under the supervision of the principal investigator.
o Other duties as assigned.

Required Qualifications:
o Ph.D., DDS, DVM, JD, MD or equivalent is required

Preferred Qualifications:
o 1-2 years of experience in Neuroscience research with animal colony handling experience preferred.

The University of Minnesota's N. Bud Grossman Center for Memory Research and Care aims to improve the lives of patients with Alzheimer's disease through development of safe and
affordable therapies that slow or prevent the onset and progression of neurological diseases affecting memory. More info on the Center: grossmanmemorycenter.umn.edu.

Pay Range: $61,008- $74,008, depending on education/qualifications/experience, per NIH guidelines.

Please visit the Benefits for Postdoctoral Candidates website for more information regarding benefit eligibility.

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training
• Medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and life insurance
• Employee wellbeing program
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

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The University of Minnesota, Twin Cities (UMTC)

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